News

January 2010
Chiralabs wishes  a Happy New Year to all!

March 2009
Chiralabs has designed and developed Diffuse Reflectance Circular Dichroism
Chiralabs has designed and developed a novel Diffuse Reflectance Circular Dichroism approach for the spectroscopic characterisation of chiral solids, suitable for the investigation of biological and bioflora samples.   

February 2009
Chiralabs extends its Biofuel analysis
Chiralabs extends its Biofuel characterisation capabilities, involving a suite of complementary FT-IR, NIR and chromatographic techniques with proprietary data analysis, for the optimisation of biodiesel production processes. 

December 2008
Collaborative work between Chiralabs and Professor George Fleet, Oxford University, is published in the journal Tetrahedron: Asymmetry (Elsevier)
The paper entitled "Carbon-branched d-tetrahydrofuran sugar amino acids (SAAs) as dipeptide isostere scaffolds" describes the synthesis of the first branched sugar amino acid.
Printed version of the full article in : Tetrahedron: Asymetry(2008), 19(24),2887-2894.

September 2008
Collaborative work between Chiralabs and Merck Serono is published in the journal BioProcess International (Informa Life Sciences Group)
The paper entitled "Higher-Order Structure Comparison of Proteins derived from Different Clones or Processes  : Unbiased assessment of Spectra by Quantitative CD" describes a  method for defining objective acceptance criteria for circular dichroism analysis of biopharmaceuticals.
Printed version of the full article in : Bioprocess International (2008), 6(8), p52-59.

September 2008
A paper on a collaborative work between Dr George Tranter and Professor George Fleet, Oxford University, has received the award of the Most Cited Paper for the 2004-2007 period in the journal Tetrahedron: Asymmetry (Elsevier)
The paper entitled "Towards hydroxylated nylon 6:Linear and cyclic oligomers from a protected 6-amino-6-deoxy-D-galactonate-A novel class of carbopeptoid-cyclodextrin (CPCD)" describes the synthesis and circular dichroism study of a class of compounds with structural features of both a cyclic peptide and a cyclodextrin.
Printed version of the full article in : Tetrahedron: asymetry(2004), 15(4), p627-638.

June 2008
Chiralabs features in Chemistry World
The activities of Chiralabs in the fields of crystallisation, solubility, chirality and biopharmaceuticals and the implications for the pharmaceutical industry are discussed:
"The physical and structural properties of drugs are of crucial importance. By rationally considering such properties as early as possible, problems can be pre-empted in drug development and manufacture – ensuring a more efficient and economical progression to market……"

February 2008
Collaborative work between Chiralabs and Professor Laurence Barron, FRS (Glasgow University) is published in the journal Biochemistry (ACS publications)
The paper entitled "Raman Optical Activity and Circular Dichroism reveal dramatic differences in the influence of divalent Copper and Manganese ions on Prion protein folding" shows the different effects Copper ions can have on the structure of the Prion protein depending on which stage they are added.
Printed version of the full article in : Biochemistry (2008), 47(8), p2510-2517.

January 2008
Chiralabs doubles its laboratory space
Chiralabs has substantially expanded its laboratories in Kidlington, Oxfordshire.  The additional laboratory space enables enhanced biopharmaceutical  analysis, particularly studies of biosimilars.  The new facilities complement Chiralab's existing chiral analysis, spectroscopic and crystallisation facilities. 

October 2007
George Tranter from Chiralabs gave a talk at the PASG Autumn 2007 meeting
The PASG meeting was held on the 8th-9th of October in Northamptonshire (UK) and focussed on New Directions: Science and Technology. The title of George Tranter's talk was  "CrystalGEM: rational crystallisation control and screening".  The effectiveness and advantages of rational crystallisation screening using CrystalGEM for pharmaceutical development were demonstrated.   

August 2007
Collaborative work between Chiralabs and Professor Laurence Barron, FRS (Glasgow University) is published online in the journal Proteins: Structure, Function & Bioinformatics (Wiley)
The paper entitled "Residual structure in disordered peptides & unfolded proteins from multivariate analysis and ab initio simulation of Raman Optical Activity data" explains how it has been possible to find the 3-dimensional folding of virus-coat proteins using the spectroscopic pattern recognition techniques developed by Chiralabs with Raman Optical Activity spectroscopy developed by Laurence Barron. Remarkably, the proteins adopt a structure that has not been found for any other class of proteins.
Printed version of the full article in : Proteins: Structure, Function & Bioinformatics (2008), 70(3), p823-833.

July 2007
Chiralabs becomes an Associate Member of the Pharmaceutical Analytical Sciences Group (PASG).

March 2007
Chiralabs signs a marketing agreement with Prosonix Ltd for the marketing of CrystalGEM®
Chiralabs agrees for Prosonix Ltd to market CrystalGEM®.

September 2006
Chiralabs  moves to new premises
Following a rapid expansion of the business in 2006, Chiralabs moves to state-of-the-art new office and laboratory space located in the Begbroke Centre for Innovation and Enterprise (Kidlington, Oxfordshire).

March 2006
The marketing MoU with C3 Technology is transfered to Prosonix Ltd (Oxford) to market CrystalGEM®
Chiralabs agrees for Prosonix Ltd to market  CrystalGEM® .

November 2005
CrystalGEM®, developed by Chiralabs, wins the Worldwide CPhI Gold Innovation Award
CrystalGEM® wins the Gold Innovation Award at the largest pharmaceutical tradeshow in the world, the CPhI, held in Madrid. CPhI is supported by 1,500 pharmaceutical and related companies from  110 countries and with 20,000 attendees.